September 26, 2026 – Aspartes Pharmaceuticals Announces Completion of Phase 1 Clinical Study Evaluating ASP-001 ODT Formulations.

PIPELINE

Our Pipeline

Aspartes’ lead drug candidate, flunarizine (ASP-001), is being developed for the treatment of alternating hemiplegia of childhood (AHC), a rare and severe neurological disorder characterized by recurrent episodes of hemiplegia and other paroxysmal neurological symptoms. ASP-001 is a novel pediatric orally disintegrating tablet formulation of flunarizine, a therapy with longstanding clinical use in AHC but no FDA-approved formulation in the United States. Our initial focus is on advancing ASP-001 through clinical development and regulatory approval for AHC, while building a broader development strategy around promising therapies for serious pediatric and rare neurological diseases supported by meaningful clinical experience and strong scientific rationale.

Program

ASP-001 - Flunarizine ODT

Alternating Hemiplegia of Childhood

ASP-002

FDA Type C Meeting Scheduled

Due Diligence

Early Clinical

Late clinical

DATA

Alternating Hemiplegia of Childhood

~ 300 - 400 patients

Estimated prevalence of AHC in the U.S.

<18 Months

Typical age of disease onset

0 FDA-Approved Treatments

Number of treatments available for AHC